Thyroid: Hashimoto’s Thyroiditis
Case 1 42 year old woman, nodular left
lobe of thyroid, lobectomy following non-diagnostic cytology. Hashimoto’s
Thyroiditis with Lymphoepithelial Cysts (Cystic Variant of Hashimoto’s).
This case showed some typical
background Hashimoto like changes but it also showed a
multicystic appearance with a
fibrous and lymphoid stroma with the cysts containing proteinaceous fluid
and cholesterol clefts. The epithelium lining the cysts
was flattened and bland without atypia. The features indicated Hashimoto’s
thyroiditis with squamous metaplasia and lymphoepithelial
cysts. There was a wide range of
differential diagnoses; intrathyroidal lymph node with epithelial inclusions, Hashimotos’ with squamous
metaplasia, Ectopic thymoma, lymphoepithelial cysts and thymic
tissue.
References
1. Cystic Variant of Hashimotos thyroiditis in Lloyd RV et al in
AFIP Atlas of Non-Tumor Pathology: Endocrine Diseases, 2002 page 123 or Carter E, Ulusarac
O.
2. Lymphoepithelial Cysts of the Thyroid Gland, Arch Pathol Lab
Med 2003:127:205-08
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